Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 9/20 | 0.75 |
| ▸ | METAP2 | P50579 | 6/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.75 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiabendazole SCHEMBL625588 | 0.87 | METAP1 (1.00) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL29370729 | 0.87 | METAP1 (1.00) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL19842 | 0.87 | METAP1 (1.00) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL11218788 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL2314460 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL27856286 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL28861440 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL9856779 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL7733801 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL5184037 | 0.85 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107910-A1 | MIXTURES OF SUCCINATE DEHYDROGENASE INHIBITORS AND PICOLINAMIDES | FMC CORPORATION (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-4361150-A2 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC Corporation (US) | 2024-05-01 | — | — | EP | disclosed |
| US-20240122180-A1 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | FMC CORPORATION | 2024-04-18 | — | — | US | disclosed |
| US-20240090503-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2024-03-21 | — | — | US | disclosed |
| EP-4262396-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC CORPORATION (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230165251-A1 | SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES | FMC CORPORATION | 2023-06-01 | — | — | US | disclosed |
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| EP-4146002-A1 | SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES | FMC CORPORATION (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-4118072-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION (US) | 2023-01-18 | — | — | EP | disclosed |
| EP-4117432-A2 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | FMC CORPORATION (US) | 2023-01-18 | — | — | EP | disclosed |
| WO-2022133114-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | FMC CORPORATION (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2021226234-A1 | SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES | FMC CORPORATION (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021183707-A2 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |
| WO-2021183721-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES. | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |
| US-4710514-A | Fungicidal carbamates and thiolcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | CYP1B1, CYP4B1, TH | METAP1 2065/4885METAP2 2645/4885NPC1 2166/4885 |
| US-20240090503-A1 | FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES | NOX1, TH, NOX3 | METAP1 2029/4885METAP2 3123/4885NPC1 1651/4885 |
| US-20240122180-A1 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES | AKR7A2, TBCA, TUBA1C | METAP1 2052/4885METAP2 2874/4885NPC1 910/4885 |
| US-20230165251-A1 | SUBSTITUTED TOLYL FUNGICIDES AND THEIR MIXTURES | NAT1, TH, Q6ZSR9 | METAP1 2439/4885METAP2 3277/4885NPC1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.