SCHEMBL10794820

SCHEMBL10794820

O=C(CCl)N1CCOC1c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
NPSR1 Q6W5P4 1/20 0.39
DRD2 P14416 2/20 0.39
SLC6A4 P31645 2/20 0.39
DRD3 P35462 1/20 0.38
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
EPHX1 P07099 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
MAPK1 P28482 1/20 0.37
PPID Q08752 1/20 0.36
PPIG Q13427 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199075 0.66 DRD2 (0.38) L3MBTL1DRD2SLC6A4DRD3HDAC3
SCHEMBL7960867 0.65 L3MBTL1 (0.50) L3MBTL1NPSR1SLC6A4KDM4EALDH1A1
SCHEMBL15393220 0.64 MAPT (0.42) NPSR1MTNR1AKDM4EMAPT
SCHEMBL8760271 0.63 HTR1A (0.56) NPSR1DRD2DRD3HTR1DHTR1B
SCHEMBL6755931 0.63 KDM4E (0.43) DRD2SLC6A4DRD3HTR1DHTR1B
SCHEMBL11638179 0.62 KMT2A (0.40) NPSR1ALDH1A1SMN1; SMN2TSHR
SCHEMBL28805535 0.62 HRH3 (0.56) DRD2SLC6A4HTR1DHTR1BEPHX1
SCHEMBL3660571 0.62 DRD2 (0.62) DRD2SLC6A4HTR1DHTR1BHRH3
SCHEMBL694466 0.62 KDM1A (0.50) L3MBTL1NPSR1DRD2SLC6A4EPHX1
SCHEMBL8747043 0.62 MTNR1A (0.50) L3MBTL1DRD2SLC6A4EPHX1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4636244-A Haloacyl and thiohaloacyl aryl-substituted oxazolidines and thiazolidines - herbicidal antidotes STAUFFER CHEMICAL CO. (US) 1987-01-13 US disclosed
US-4483706-A PLANT SAFENING AGENTS STAUFFER CHEMICAL COMPANY (US) 1984-11-20 US disclosed
US-4400200-A PLANT SAFENING AGENTS STAUFFER CHEMICAL COMPANY (US) 1983-08-23 US disclosed
US-4322240-A Haloacyl and thiohaloacyl aryl-substituted oxazolidines and thiazolidines-herbicidal antidotes STAUFFER CHEMICAL COMPANY (US) 1982-03-30 US disclosed
US-4072688-A Haloacyl and thiohaloacyl aryl-substituted oxazolidines and thiazolidines-herbicidal antidotes STAUFFER CHEMICAL COMPANY (US) 1978-02-07 US disclosed