Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942169 | 0.69 | RBP4 (0.50) | KCNH2SMN1; SMN2CYP2D6ALDH1A1POLB | |
| SCHEMBL4513322 | 0.68 | DRD3 (0.46) | — | |
| SCHEMBL14562462 | 0.67 | HTR2C (0.53) | HTR2AHTR2CHTR2BTERTNPSR1 | |
| SCHEMBL1558330 | 0.66 | DRD2 (0.66) | — | |
| SCHEMBL18642715 | 0.65 | L3MBTL1 (0.51) | L3MBTL1KDM4E | |
| SCHEMBL5055418 | 0.65 | AR (0.38) | HTR2AHTR2CHTR2BCYP2D6MAOA | |
| SCHEMBL2048903 | 0.64 | HTR2A (0.44) | L3MBTL1TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL20710319 | 0.64 | RIPK1 (0.63) | L3MBTL1TSHRALDH1A1POLBADRB2 | |
| SCHEMBL20710310 | 0.64 | RIPK1 (0.63) | L3MBTL1TSHRALDH1A1POLBADRB2 | |
| SCHEMBL27820532 | 0.64 | TERT (0.40) | HTR2AHTR2CHTR2BMAPTTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310058-B1 | N-HYDROXYAZEPIN-2-ONES SUBSTITUTED AT 3 POSITION WITH A GROUP CONTAINING A 2-PHENYLOXAZOLE OR 2-PHENYLOXAZOLINE GROUP FOR TREATING TUBERCULOSIS | UNIVERSITY OF NOTRE DAME DU LAC | 2001-10-30 | — | — | US | disclosed |