Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chloramphenicol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPLP1 | P05386 | 1/20 | 1.00 |
| ▸ | RPLP0 | P05388 | 1/20 | 1.00 |
| ▸ | RPS17 | P08708 | 1/20 | 1.00 |
| ▸ | RPSA | P08865 | 1/20 | 1.00 |
| ▸ | RPS2 | P15880 | 1/20 | 1.00 |
| ▸ | RPL35A | P18077 | 1/20 | 1.00 |
| ▸ | RPL7 | P18124 | 1/20 | 1.00 |
| ▸ | RPL17 | P18621 | 1/20 | 1.00 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 1.00 |
| ▸ | RPS3 | P23396 | 1/20 | 1.00 |
| ▸ | RPS12 | P25398 | 1/20 | 1.00 |
| ▸ | RPL13 | P26373 | 1/20 | 1.00 |
| ▸ | RPL10 | P27635 | 1/20 | 1.00 |
| ▸ | RPL12 | P30050 | 1/20 | 1.00 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 1.00 |
| ▸ | RPL22 | P35268 | 1/20 | 1.00 |
| ▸ | RPL4 | P36578 | 1/20 | 1.00 |
| ▸ | RPS19 | P39019 | 1/20 | 1.00 |
| ▸ | RPL3 | P39023 | 1/20 | 1.00 |
| ▸ | RPL13A | P40429 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloramphenicol SCHEMBL49057 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL537158 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL29557257 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL28181476 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL4295048 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL16111 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL4262903 | 0.95 | LMNA (1.00) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL11131056 | 0.94 | LMNA (0.97) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL41042 | 0.94 | LMNA (0.97) | RPLP1RPLP0RPS17RPSARPS2 | |
| Chloramphenicol SCHEMBL20531030 | 0.94 | LMNA (0.97) | RPLP1RPLP0RPS17RPSARPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897452-B1 | RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS | TEPHA INC (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20230201610-A1 | RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS | TEPHA, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-11612754-B2 | Resorbable nonwoven pouches for medical device implants | TEPHA, INC. (US) | 2023-03-28 | — | — | US | disclosed |
| CN-114858875-A | Method for detecting kanamycin through self-enhanced photoelectrochemistry | 青岛科技大学 | 2022-08-05 | — | — | CN | disclosed |
| EP-3897452-A1 | RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS | Tepha, Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3743089-A1 | METHOD OF TREATING BENIGN PROSTATIC HYPERLASIA WITH ANTIBIOTICS | Nymox Corporation (US) | 2020-12-02 | — | — | EP | disclosed |
| US-10835538-B2 | Method of treating benign prostatic hyperlasia with antibiotics | NYMOX CORPORATION (BS) | 2020-11-17 | — | — | US | disclosed |
| US-20200197712-A1 | RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS | TEPHA, INC. | 2020-06-25 | — | — | US | disclosed |
| WO-2020131172-A1 | RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS | TEPHA, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20190298731-A1 | METHOD OF TREATING BENIGN PROSTATIC HYPERLASIA WITH ANTIBIOTICS | NYMOX CORPORATION | 2019-10-03 | — | — | US | disclosed |
| WO-2019191253-A1 | METHOD OF TREATING BENIGN PROSTATIC HYPERLASIA WITH ANTIBIOTICS | NYMOX CORPORATION (US) | 2019-10-03 | — | — | WO | disclosed |
| US-4642104-A | Urethral catheter capable of preventing urinary tract infection and process for producing the same | UNITIKA LTD. (JP) | 1987-02-10 | — | — | US | disclosed |
| EP-0065884-B1 | URETHRAL CATHETER CAPABLE OF PREVENTING URINARY TRACT INFECTION AND PROCESS FOR PRODUCING THE SAME | UNITIKA LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4539234-A | Urethral catheter capable of preventing urinary tract infection and process for producing the same | UNITIKA LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0065884-A1 | Urethral catheter capable of preventing urinary tract infection and process for producing the same | UNITIKA LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |