Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chloramphenicol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.90 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.90 |
| ▸ | RPS17 | P08708 | 1/20 | 0.90 |
| ▸ | RPSA | P08865 | 1/20 | 0.90 |
| ▸ | RPS2 | P15880 | 1/20 | 0.90 |
| ▸ | RPL35A | P18077 | 1/20 | 0.90 |
| ▸ | RPL7 | P18124 | 1/20 | 0.90 |
| ▸ | RPL17 | P18621 | 1/20 | 0.90 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.90 |
| ▸ | RPS3 | P23396 | 1/20 | 0.90 |
| ▸ | RPS12 | P25398 | 1/20 | 0.90 |
| ▸ | RPL13 | P26373 | 1/20 | 0.90 |
| ▸ | RPL10 | P27635 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloramphenicol SCHEMBL4262903 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL28181476 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL16111 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL29557257 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL4295048 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL537158 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL11131056 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL41042 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL20531030 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL28607485 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13365 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250172561-A1 | PROBE FOR UNIVERSAL DETECTION OF CIRCULATING TUMOR CELLS | UNIV HOUSTON SYSTEM (US) | 2025-05-29 | — | — | US | claimed |
| US-20250164490-A1 | PROBE FOR UNIVERSAL DETECTION OF CIRCULATING TUMOR CELLS | UNIV HOUSTON SYSTEM (US) | 2025-05-22 | — | — | US | claimed |
| WO-2025032060-A1 | CRISPR-COACERVATE SYSTEM | ETH ZURICH (CH) | 2025-02-13 | — | — | WO | claimed |
| EP-4506464-A1 | CRISPR-COACERVATE SYSTEM | ETH Zurich (CH) | 2025-02-12 | — | — | EP | claimed |
| EP-3756665-B1 | INTERVAL THERAPY FOR THE TREATMENT OF EYE DISEASES | UNIV RAMOT (IL) | 2024-08-14 | — | — | EP | claimed |
| US-20240041976-A1 | COMPOSITION AND USE | NORWEGIAN UNIVERSITY OF LIFE SCIENCES (NO) | 2024-02-08 | — | — | US | claimed |
| US-20230404983-A1 | COMPOSITIONS, DEVICES AND METHODS FOR TREATING OBSESSIVE-COMPULSIVE DISORDER | CENTRE FOR DIGESTIVE DISEASES (AU) | 2023-12-21 | — | — | US | claimed |
| CN-114377117-B | Oral type 1diabetes vaccine and preparation method thereof | 中国医学科学院医学生物学研究所 | 2023-11-10 | — | — | CN | claimed |
| CN-116782865-A | Atomic layer deposition coated pharmaceutical packages, improved syringes and vials, e.g., for lyophilization/cold chain drugs/vaccines | SIO2医药产品公司 | 2023-09-19 | — | — | CN | claimed |
| WO-2023144127-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR BIODISTRIBUTION UPON ADMINISTRATION, AND USES | AGS THERAPEUTICS SAS (FR) | 2023-08-03 | — | — | WO | claimed |
| EP-0092388-B1 | CLONING VECTORS | ELI LILLY AND COMPANY (US) | 1990-07-04 | — | — | EP | claimed |
| CN-1041182-A | ANTIBIOTIC GE 2270 | LEPETIT SPA (IT) | 1990-04-11 | — | — | CN | claimed |
| CN-1006226-B | Non-toxic neoprene adhesive | 李书清 | 1989-12-27 | — | — | CN | claimed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |
| US-4849227-A | Pharmaceutical compositions | EURASIAM LABORATORIES, INC. (US) | 1989-07-18 | — | — | US | claimed |
| CN-87107233-A | Genetic engineering of cotton plants and strains thereof | — | 1988-08-24 | — | — | CN | claimed |
| CN-86107908-A | Directly DNA is inserted plastid and plastosome | — | 1987-09-30 | — | — | CN | claimed |
| US-4478822-A | Drug delivery system utilizing thermosetting gels | MERCK & CO., INC. (US) | 1984-10-23 | — | — | US | claimed |
| EP-0010846-B1 | METHOD AND APPARATUS FOR DETERMINING THE MINIMUM CONCENTRATION OF ANTIBIOTIC TO INHIBIT MICROORGANISM GROWTH | WARNER-LAMBERT COMPANY (US) | 1982-09-15 | — | — | EP | claimed |
| US-4322398-A | Implantable drug depot and process for the production thereof | BATTELLE INSTITUT E.V. (DE) | 1982-03-30 | — | — | US | claimed |