Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chloramphenicol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.90 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.90 |
| ▸ | RPS17 | P08708 | 1/20 | 0.90 |
| ▸ | RPSA | P08865 | 1/20 | 0.90 |
| ▸ | RPS2 | P15880 | 1/20 | 0.90 |
| ▸ | RPL35A | P18077 | 1/20 | 0.90 |
| ▸ | RPL7 | P18124 | 1/20 | 0.90 |
| ▸ | RPL17 | P18621 | 1/20 | 0.90 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.90 |
| ▸ | RPS3 | P23396 | 1/20 | 0.90 |
| ▸ | RPS12 | P25398 | 1/20 | 0.90 |
| ▸ | RPL13 | P26373 | 1/20 | 0.90 |
| ▸ | RPL10 | P27635 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloramphenicol SCHEMBL4262903 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL28181476 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL49057 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL16111 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL4295048 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL537158 | 1.00 | LMNA (1.00) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL11131056 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL41042 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL20531030 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Chloramphenicol SCHEMBL28607485 | 0.99 | LMNA (0.97) | LMNACYP3A4TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114886877-A | Olanzapine fluoxetine compound oral solution and preparation method thereof | 北京海泰天正医药科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| US-12421475-B2 | High performing, high impact bloom accord with a top, medium, and base note mixture | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12419815-B2 | Microcapsule compositions stabilized with viscosity control agents | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12357547-B2 | Compositions containing microcapsules | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-12324452-B2 | Delivery systems and methods of preparing the same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-06-10 | — | — | US | disclosed |
| US-12274771-B2 | Polyurea capsule compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2025-04-15 | — | — | US | disclosed |
| CN-119821018-A | System and method for printing and drying fragrances and perfumes | 国际香料和香精公司 | 2025-04-15 | — | — | CN | disclosed |
| US-12030326-B2 | System and method for printing and drying flavors and fragrances | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230337707-A1 | MICROENCAPSULATION WITH PLANT PROTEIN | INT FLAVORS & FRAGRANCES INC (US) | 2023-10-26 | — | — | US | disclosed |
| CN-116764558-A | Microcapsule compositions stabilized with viscosity control agents | 国际香料和香精公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-3512625-B1 | MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS | INT FLAVORS & FRAGRANCES INC (US) | 2023-04-26 | — | — | EP | disclosed |
| EP-4149280-A1 | ROBUST FLAVOR EMULSIONS | International Flavors & Fragrances Inc. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-11602494-B2 | Compositions containing microcapsules coated with deposition proteins | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2023-03-14 | — | — | US | disclosed |
| EP-4093211-A1 | MICROENCAPSULATION WITH PLANT PROTEIN | International Flavors & Fragrances Inc. (US) | 2022-11-30 | — | — | EP | disclosed |
| CN-115058289-A | High performance, high impact strength fragrance emitting accord | 国际香料和香精公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-107362157-B | Ophthalmic pharmaceutical composition for use in medicine and veterinary medicine | 米拓科技有限公司（卢森堡） | 2022-08-26 | — | — | CN | disclosed |
| CN-109803632-B | High performance, high impact strength fragrance emitting accord | 国际香料和香精公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114471660-A | MXenes composite material and preparation method and application thereof | 东莞理工学院 | 2022-05-13 | — | — | CN | disclosed |
| US-11326126-B2 | High performing, high impact bloom accord | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-05-10 | — | — | US | disclosed |
| US-20220095659-A1 | MICROENCAPSULATION WITH POTATO PROTEINS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12357547-B2 | Compositions containing microcapsules | COPE, SAAL1, AUP1 | LMNA 1268/4885CYP3A4 4727/4885TSHR 3290/4885 |
| US-12324452-B2 | Delivery systems and methods of preparing the same | MAL2, TAS2R42, TAS2R31 | LMNA 1592/4885CYP3A4 244/4885TSHR 2243/4885 |
| US-12419815-B2 | Microcapsule compositions stabilized with viscosity control agents | ACR, ALG1, MLEC | LMNA 796/4885CYP3A4 4816/4885TSHR 3885/4885 |
| US-11602494-B2 | Compositions containing microcapsules coated with deposition proteins | AUP1, CAPG, TTR | LMNA 1665/4885CYP3A4 4856/4885TSHR 3606/4885 |
| US-12274771-B2 | Polyurea capsule compositions | PUF60, UMPS, PCBP1 | LMNA 2486/4885CYP3A4 4742/4885TSHR 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.