Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012934 | 0.85 | KMT2A (0.43) | NR3C1 | |
| SCHEMBL5800398 | 0.75 | — | — | |
| SCHEMBL10797975 | 0.73 | DPYD (0.46) | — | |
| SCHEMBL9103862 | 0.71 | KDM6B (0.42) | NR3C1 | |
| SCHEMBL3219893 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL3787961 | 0.69 | FDPS (0.47) | — | |
| Hydrochloric Acid SCHEMBL2745314 | 0.68 | ALDH1A1 (0.42) | — | |
| SCHEMBL5353422 | 0.68 | GPR84 (0.59) | — | |
| SCHEMBL4353311 | 0.67 | DPYD (0.50) | — | |
| SCHEMBL11064646 | 0.67 | NR3C1 (0.35) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675406-A | Substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| US-4620001-A | Chemical methods and intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1986-10-28 | — | — | US | disclosed |
| US-4477663-A | Intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4352933-A | Chemical methods and intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |