Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10794531 | 0.99 | ALDH1A1 (0.44) | ALDH1A1ACHEAPLNRHSD11B1LMNA | |
| SCHEMBL10800250 | 0.85 | HTR6 (0.49) | APLNRCCR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL10794724 | 0.84 | HTR6 (0.48) | APLNRCCR6HTR2AHTR2C | |
| SCHEMBL10794767 | 0.83 | APLNR (0.47) | APLNR | |
| SCHEMBL10795613 | 0.83 | APLNR (0.47) | ALDH1A1ACHEAPLNRGAA | |
| Hydrochloric Acid SCHEMBL10800304 | 0.82 | APLNR (0.46) | APLNR | |
| SCHEMBL270534 | 0.81 | HSD11B1 (0.47) | ALDH1A1ACHEHSD11B1LMNAGAA | |
| SCHEMBL271335 | 0.81 | LMNA (0.51) | ALDH1A1ACHEHSD11B1LMNAGAA | |
| SCHEMBL10795010 | 0.80 | APLNR (0.47) | ALDH1A1APLNRGAA | |
| SCHEMBL10799201 | 0.80 | APLNR (0.47) | APLNRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642348-A | ANTIARRHYTHMIA AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-02-10 | — | — | US | disclosed |
| US-4593102-A | N-[(amino)alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulfur linked substitution in the 2, 3 or 4-position | A. H. ROBINS COMPANY, INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0160436-A2 | N-[(Amino)Alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulphur linked substitution in the 2, 3 or 4-position | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-11-06 | — | — | EP | disclosed |