SCHEMBL841998

SCHEMBL841998

Cc1cc(C)c(S(=O)(=O)n2ccnc2)c(C)c1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
HTT P42858 2/20 0.55
FABP4 P15090 1/20 0.55
LMNA P02545 2/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
RAPGEF4 Q8WZA2 5/20 0.48
TP53 P04637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23699006 0.83 TSHR (0.58) TSHRHTTFABP4LMNAMEN1
SCHEMBL10801457 0.76 SMN1; SMN2 (0.65) TSHRHTTFABP4LMNAMEN1
SCHEMBL217862 0.74 TP53 (0.69) TSHRHTTFABP4LMNAMEN1
Ammonia Solution, Strong SCHEMBL28097128 0.72 TP53 (0.67) TSHRHTTFABP4LMNAMEN1
1-Methylimidazole SCHEMBL6445728 0.72 LMNA (0.48) TSHRHTTFABP4LMNAMEN1
SCHEMBL4727160 0.71 HTT (0.57) TSHRHTTFABP4LMNAMEN1
SCHEMBL840945 0.71 FABP4 (1.00) TSHRHTTFABP4LMNAMEN1
SCHEMBL9108321 0.71 FABP4 (1.00) TSHRHTTFABP4LMNAMEN1
SCHEMBL10798648 0.70 TSHR (0.58) TSHRHTTFABP4LMNAMEN1
SCHEMBL3239413 0.70 TSHR (0.58) TSHRHTTFABP4LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
US-5140055-A Improved high speed grip performance BRIDGESTONE CORPORATION (JP) 1992-08-18 US claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP claimed
CN-118239890-A Ionic liquid shale inhibitor and preparation method and application thereof 中国石油天然气集团有限公司 2024-06-25 CN disclosed
CN-104448700-B Resin combination 味之素株式会社 2019-01-22 CN disclosed
CN-104448700-A Resin composition AJINOMOTO KK 2015-03-25 CN disclosed
CN-102007185-B Gas barrier composition, coating film, method for producing the gas barrier composition, method for producing the coating film, and multilayer body MITSUI CHEMICALS INC 2013-04-24 CN disclosed
CN-101171297-B Gas barrier composition, coating film, method for producing same, and laminate MITSUI CHEMICALS INC 2012-04-25 CN disclosed
US-8143413-B2 Polycationized phospholipid derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-03-27 US disclosed
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US disclosed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US disclosed
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 EP disclosed
US-5244762-A Polymers of hydroxyacrylic amides and hydroxyacrylic esters, hydroxy group modified to become ether, ester, sulfonate, carbamate XEROX CORPORATION (US) 1993-09-14 US disclosed
US-5242892-A With 5-aminolevulinic acid THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1993-09-07 US disclosed
US-5140055-A Improved high speed grip performance BRIDGESTONE CORPORATION (JP) 1992-08-18 US disclosed
EP-0251760-A2 Rubber composition Bridgestone Corporation (JP) 1988-01-07 EP disclosed