SCHEMBL15533401

SCHEMBL15533401

CC1CCC(C(C)C)C(Oc2ccccc2NC(=O)C2CC(C)CCC2C(C)C)C1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 5/20 0.55
P2RX4 Q99571 1/20 0.53
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
SCN9A Q15858 1/20 0.43
EPHX1 P07099 3/20 0.42
ACLY P53396 1/20 0.41
CYP19A1 P11511 2/20 0.41
MEN1 O00255 1/20 0.40
NTSR1 P30989 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4963208 0.87 TRPM8 (0.64) TRPM8P2RX4EPHX1
SCHEMBL10072942 0.87 TRPM8 (0.64) TRPM8P2RX4EPHX1
SCHEMBL2628761 0.81 TRPM8 (0.58) TRPM8P2RX4ALDH1A1HPGDLMNA
SCHEMBL2628773 0.81 TRPM8 (0.58) TRPM8P2RX4ALDH1A1HPGDEPHX1
SCHEMBL4812089 0.81 P2RX4 (0.61) TRPM8P2RX4ALDH1A1HPGDEPHX1
SCHEMBL10799486 0.81 NPC1 (0.53) TRPM8P2RX4ALDH1A1HPGDLMNA
SCHEMBL2628771 0.80 TRPM8 (0.57) TRPM8P2RX4ALDH1A1EPHX1MEN1
SCHEMBL2628744 0.80 TRPM8 (0.60) TRPM8P2RX4EPHX1
SCHEMBL4886225 0.80 TRPM8 (0.60) TRPM8P2RX4ALDH1A1HPGDKMT2A
SCHEMBL15533403 0.80 TRPM8 (0.77) TRPM8P2RX4ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872109-A2 PERSONAL CARE COMPOSITION COMPRISING A COLLING ACTIVE AND A COPOLYMER COMPRISING ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE Unilever N.V. (NL) 2015-05-20 EP claimed
WO-2013174615-A2 PERSONAL CARE COMPOSITION UNILEVER N.V. (NL) 2013-11-28 WO claimed
US-20250262137-A1 Films and Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2025-08-21 US disclosed
EP-4392005-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2024-07-03 EP disclosed
US-20230390164-A1 Films and Oral Care Compositions Comprising Same COLGATE-PALMOLIVE COMPANY (US) 2023-12-07 US disclosed
EP-4199880-A1 FILMS AND ORAL CARE COMPOSITIONS COMPRISING SAME Colgate-Palmolive Company (US) 2023-06-28 EP disclosed
EP-4199889-A1 FILMS AND ORAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2023-06-28 EP disclosed
WO-2023107659-A1 PERSONAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2023-06-15 WO disclosed
US-20230181445-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-06-15 US disclosed
WO-2022094233-A1 FILMS AND ORAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2022-05-05 WO disclosed
WO-2022094212-A1 FILMS AND ORAL CARE COMPOSITIONS COMPRISING SAME COLGATE-PALMOLIVE COMPANY (US) 2022-05-05 WO disclosed
CN-109010128-B Personal care compositions comprising a cooling active and a copolymer containing acrylamidopropyltrimethylammonium chloride 联合利华知识产权控股有限公司 2021-12-21 CN disclosed
US-10463597-B2 Personal care composition CONOPCO, INC. (US) 2019-11-05 US disclosed
EP-2872109-B1 PERSONAL CARE COMPOSITION COMPRISING A COOLING ACTIVE AND A COPOLYMER COMPRISING ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE UNILEVER NV (NL) 2017-06-14 EP disclosed
EP-2872109-A2 PERSONAL CARE COMPOSITION COMPRISING A COLLING ACTIVE AND A COPOLYMER COMPRISING ACRYLAMIDOPROPYLTRIMONIUM CHLORIDE Unilever N.V. (NL) 2015-05-20 EP disclosed
US-20150110728-A1 PERSONAL CARE COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2015-04-23 US disclosed
WO-2013174615-A2 PERSONAL CARE COMPOSITION UNILEVER N.V. (NL) 2013-11-28 WO disclosed