Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925579 | 0.85 | KDM4E (0.55) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL13574288 | 0.80 | ALOX5 (0.41) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL21123646 | 0.80 | GAA (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10172892 | 0.80 | CSNK2A1 (0.59) | ACE2 | |
| SCHEMBL17707907 | 0.78 | FABP3 (0.52) | MEN1KMT2ATDP1RECQLMCL1 | |
| SCHEMBL11805203 | 0.78 | CA12 (0.55) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1355684 | 0.78 | ACE2 (0.67) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL24680076 | 0.77 | KDM4E (0.53) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL17465967 | 0.77 | KEAP1 (0.53) | RECQLACE2FABP3FABP4 | |
| SCHEMBL17465965 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642240-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |