Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795932 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTNPC1HDAC1HDAC6 | |
| SCHEMBL10801436 | 0.81 | L3MBTL1 (0.54) | ALDH1A1MAPTNPC1HDAC1HDAC6 | |
| SCHEMBL20583292 | 0.79 | GAA (0.71) | ALDH1A1NPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL9795959 | 0.79 | GAA (0.71) | ALDH1A1NPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL9795955 | 0.79 | GAA (0.71) | ALDH1A1NPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL20582091 | 0.78 | MAPT (0.43) | ALDH1A1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL14938560 | 0.74 | MAPT (0.78) | ALDH1A1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL19779264 | 0.74 | HDAC1 (0.48) | ALDH1A1MAPTNPC1HDAC1HDAC6 | |
| SCHEMBL31290288 | 0.74 | HDAC1 (0.62) | ALDH1A1MAPTNPC1HDAC1HDAC6 | |
| SCHEMBL181465 | 0.74 | HDAC1 (0.62) | ALDH1A1MAPTHDAC1HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |