Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804730 | 0.77 | L3MBTL1 (0.53) | NSD2TDP1L3MBTL1HPGDIDO1 | |
| SCHEMBL7981204 | 0.71 | CTNNB1 (0.60) | L3MBTL1IDO1RAB9ANPC1GAA | |
| SCHEMBL28408612 | 0.71 | RAB9A (0.71) | L3MBTL1HPGDIDO1RAB9ANPC1 | |
| SCHEMBL6877854 | 0.70 | IDO1 (0.54) | L3MBTL1IDO1RAB9ANPC1ALDH1A1 | |
| SCHEMBL30454690 | 0.70 | RAB9A (0.60) | L3MBTL1IDO1RAB9ANPC1ALDH1A1 | |
| SCHEMBL10412713 | 0.70 | RAB9A (0.60) | L3MBTL1IDO1RAB9ANPC1ALDH1A1 | |
| SCHEMBL2051943 | 0.70 | RAB9A (0.75) | TDP1HPGDIDO1RAB9ANPC1 | |
| SCHEMBL6011931 | 0.70 | RAB9A (0.75) | TDP1HPGDIDO1RAB9ANPC1 | |
| Iodide SCHEMBL28448392 | 0.69 | RAB9A (0.69) | L3MBTL1HPGDIDO1RAB9ANPC1 | |
| SCHEMBL29828134 | 0.69 | ALDH1A1 (0.61) | TDP1IDO1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079049-B1 | NOVEL SUBSTITUTED ALKANOYLIMIDAZOL-2-ONE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-01 | — | — | EP | disclosed |
| US-4447619-A | CARDIOTONIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0079049-A2 | Novel substituted alkanoylimidazol-2-one derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4367236-A | CARDIOTONIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-01-04 | — | — | US | disclosed |