Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810642 | 0.83 | KDM4E (0.41) | FFAR4PDE5AALDH1A1MAPTKDM4E | |
| SCHEMBL10808457 | 0.83 | KDM4E (0.41) | FFAR4PDE5AALDH1A1MAPTKDM4E | |
| SCHEMBL10812819 | 0.81 | PDE5A (0.41) | FFAR4PDE5AALDH1A1MAPTHPGD | |
| SCHEMBL10809218 | 0.79 | NPC1 (0.42) | FFAR4PDE5AALDH1A1MAPTKDM4E | |
| SCHEMBL7879779 | 0.78 | FFAR4 (0.47) | FFAR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7877547 | 0.76 | CDK1 (0.47) | FFAR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10510005 | 0.74 | SRD5A2 (0.43) | FFAR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4047141 | 0.74 | RAB9A (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31501880 | 0.74 | RAB9A (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20944325 | 0.74 | GABRA1 (0.64) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079637-B1 | ANTI-SRS-A CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL FORMULATION CONTAINING THEM | FISONS plc (GB) | 1987-01-28 | — | — | EP | disclosed |
| US-4474788-A | Anti-SRSA quinoline carboxylic acid derivatives | FISONS PLC (GB) | 1984-10-02 | — | — | US | disclosed |
| EP-0079637-A1 | Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them | FISONS plc (GB) | 1983-05-25 | — | — | EP | disclosed |