Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872378 | 0.83 | MEN1 (0.41) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL10814733 | 0.77 | CYP3A4 (0.37) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL7398888 | 0.73 | LMNA (0.31) | LMNA | |
| SCHEMBL4620126 | 0.72 | — | — | |
| SCHEMBL9226961 | 0.72 | SPHK2 (0.39) | — | |
| SCHEMBL473627 | 0.71 | FFAR1 (0.41) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL29163241 | 0.69 | OPRM1 (0.38) | LMNA | |
| SCHEMBL28105635 | 0.69 | LMNA (0.36) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL24296723 | 0.69 | ALDH1A1 (0.41) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL1298190 | 0.69 | MEN1 (0.41) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129211-B1 | 2,6-TRANS-DIMETHYL MORPHOLINE DERIVATIVES, FUNGICIDES CONTAINING THEM AND METHODS OF COMBATING FUNGI | BASF Aktiengesellschaft (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0129211-A1 | 2,6-Trans-dimethyl morpholine derivatives, fungicides containing them and methods of combating fungi | BASF Aktiengesellschaft (DE) | 1984-12-27 | — | — | EP | disclosed |