Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814733 | 0.88 | CYP3A4 (0.37) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL29163241 | 0.84 | OPRM1 (0.38) | LMNA | |
| SCHEMBL10814728 | 0.83 | MEN1 (0.38) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL473627 | 0.81 | FFAR1 (0.41) | MEN1CYP3A4ALOX15KMT2ABLM | |
| SCHEMBL10922168 | 0.80 | — | — | |
| SCHEMBL28105635 | 0.80 | LMNA (0.36) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL24296723 | 0.80 | ALDH1A1 (0.41) | MEN1CYP3A4ALOX15KMT2AALDH1A1 | |
| SCHEMBL22268914 | 0.80 | LMNA (0.32) | MEN1KMT2ALMNA | |
| SCHEMBL1298190 | 0.79 | MEN1 (0.41) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL9793534 | 0.77 | MEN1 (0.44) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026473-B2 | Process for the carbonylation of pentenenitrile | SHELL OIL COMPANY (US) | 2006-04-11 | — | — | US | disclosed |