Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826081 | 0.85 | GOT1 (0.38) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| Hydrochloric Acid SCHEMBL11824418 | 0.83 | GOT1 (0.38) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| SCHEMBL11825782 | 0.80 | AOC1 (0.38) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| SCHEMBL11833130 | 0.80 | AOC1 (0.38) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| Hydrochloric Acid SCHEMBL11496984 | 0.78 | AOC1 (0.40) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| SCHEMBL11822171 | 0.78 | KDM4E (0.43) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| SCHEMBL11834774 | 0.77 | KDM6B (0.36) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| SCHEMBL11823547 | 0.76 | LMNA (0.43) | GOT1PTGS1SMN1; SMN2LMNARAB9A | |
| SCHEMBL11819181 | 0.76 | KDM6B (0.38) | GOT1ALDH1A1MAOAPTGS1KDM4E | |
| Hydrochloric Acid SCHEMBL11821377 | 0.74 | KDM6B (0.37) | GOT1ALDH1A1MAOAPTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097202-B1 | HYDRAZINOPYRIDAZINE COMPOUND, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENT | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1987-11-19 | — | — | EP | claimed |
| EP-0097202-B1 | HYDRAZINOPYRIDAZINE COMPOUND, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENT | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0097202-A1 | Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1984-01-04 | — | — | EP | disclosed |