Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822171 | 0.83 | KDM4E (0.43) | LMNAPTGS1PTGS2MAPTGAA | |
| SCHEMBL11823585 | 0.81 | GAA (0.51) | LMNAPTGS1PTGS2TTBK1TTBK2 | |
| SCHEMBL11827688 | 0.80 | EPHX2 (0.41) | TTBK1MAPTSCN9AGAAMEN1 | |
| SCHEMBL11825813 | 0.80 | PTGS1 (0.44) | LMNAPTGS1PTGS2MAPTMAPKAPK2 | |
| SCHEMBL11822532 | 0.77 | MAPT (0.46) | LMNAMKNK1TTBK1TTBK2MAPT | |
| SCHEMBL10817008 | 0.76 | GOT1 (0.41) | LMNAPTGS1MAPTGAAGOT1 | |
| SCHEMBL11826081 | 0.71 | GOT1 (0.38) | LMNAPTGS1MAPTGOT1ADORA3 | |
| SCHEMBL3246534 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11824418 | 0.69 | GOT1 (0.38) | LMNAPTGS1MAPTGOT1ADORA3 | |
| SCHEMBL28369905 | 0.69 | HSD17B10 (0.42) | LMNAPTGS1PTGS2TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |