Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | GOT1 | P17174 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369905 | 0.87 | HSD17B10 (0.42) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL11823547 | 0.83 | LMNA (0.43) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL11823585 | 0.80 | GAA (0.51) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL11825813 | 0.79 | PTGS1 (0.44) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL11827688 | 0.79 | EPHX2 (0.41) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL10817008 | 0.78 | GOT1 (0.41) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL11826081 | 0.73 | GOT1 (0.38) | KDM4EMAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL11823327 | 0.72 | ALDH1A1 (0.46) | KDM4EMAPTGAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11824418 | 0.72 | GOT1 (0.38) | KDM4EMAPTALDH1A1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL11823944 | 0.71 | ALDH1A1 (0.45) | KDM4EMAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |