Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GHSR | Q92847 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823480 | 0.88 | MAPT (0.50) | LMNACA12CA1CA2CA9 | |
| SCHEMBL10823479 | 0.87 | HSD17B2 (0.46) | LMNAGHSRCA12CA1CA2 | |
| SCHEMBL10823616 | 0.85 | IDH1 (0.57) | — | |
| SCHEMBL10823574 | 0.84 | CA12 (0.45) | GHSRCA12CA1CA2CA9 | |
| SCHEMBL10823663 | 0.83 | LMNA (0.47) | LMNAGHSRGAAMEN1KMT2A | |
| SCHEMBL10823342 | 0.83 | KMT2A (0.45) | LMNAGHSRCA12CA1CA2 | |
| SCHEMBL10823478 | 0.82 | LMNA (0.52) | LMNAGHSRCA2HSD17B2GAA | |
| SCHEMBL10823709 | 0.82 | LMNA (0.52) | LMNAGHSRCA2HSD17B2HKDC1 | |
| SCHEMBL11339195 | 0.81 | TIMP3 (0.48) | MPLSNCAPRMT1 | |
| SCHEMBL10823484 | 0.81 | IDH1 (0.52) | LMNACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |