Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823744 | 0.91 | PRMT1 (0.44) | PTGESMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10823553 | 0.86 | PTGES (0.50) | PTGESMEN1KMT2ATRPV1ALDH1A1 | |
| SCHEMBL10823437 | 0.84 | CASP6 (0.44) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL10823390 | 0.83 | HKDC1 (0.46) | PTGESMEN1KMT2APRMT1CA12 | |
| SCHEMBL10823352 | 0.83 | PTGES (0.41) | PTGESMEN1KMT2AALDH1A1CYTH2 | |
| SCHEMBL10823506 | 0.83 | PRMT1 (0.45) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL10823443 | 0.83 | MEN1 (0.44) | PTGESMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11339174 | 0.83 | HPSE (0.46) | MEN1KMT2ATRPV1ALDH1A1MAPT | |
| SCHEMBL10823596 | 0.81 | TRPV1 (0.51) | MEN1KMT2ATRPV1MAPTPRMT1 | |
| SCHEMBL10823686 | 0.81 | IDH1 (0.52) | PTGESPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |