Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823757 | 0.94 | PRMT1 (0.62) | PRMT1SIRT1CASP6CTDSP1NSD2 | |
| SCHEMBL10823369 | 0.92 | NT5E (0.47) | PRMT1SIRT1CASP6NSD2DUSP3 | |
| SCHEMBL10823506 | 0.84 | PRMT1 (0.45) | PRMT1SIRT1CASP6CA12CA1 | |
| SCHEMBL10823390 | 0.84 | HKDC1 (0.46) | PRMT1CASP6CA12CA1CA2 | |
| SCHEMBL10823609 | 0.83 | PRMT1 (0.73) | PRMT1SIRT1CASP6CTDSP1NSD2 | |
| SCHEMBL11344912 | 0.83 | CASP6 (0.56) | PRMT1SIRT1CASP6CTDSP1NSD2 | |
| SCHEMBL10823437 | 0.83 | CASP6 (0.44) | PRMT1CASP6NT5EMEN1MAPT | |
| SCHEMBL10823779 | 0.82 | EP300 (0.49) | PRMT1CA12CA1CA2CA9 | |
| SCHEMBL10823345 | 0.82 | PRMT1 (0.67) | PRMT1SIRT1CASP6CTDSP1CA12 | |
| SCHEMBL10823349 | 0.82 | IDH1 (0.43) | CA12CA1CA2CA9IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |