Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823435 | 0.90 | KMT2A (0.52) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL10823667 | 0.86 | MEN1 (0.44) | MEN1KMT2ALMNAHTTNAMPT | |
| SCHEMBL10823386 | 0.85 | TIMP3 (0.47) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL10823454 | 0.84 | CA12 (0.41) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL10823698 | 0.83 | PRMT1 (0.55) | MEN1KMT2ALMNAHTTNAMPT | |
| SCHEMBL10823663 | 0.83 | LMNA (0.47) | MEN1KMT2ALMNAHTTNAMPT | |
| SCHEMBL10823759 | 0.83 | MEN1 (0.46) | MEN1KMT2ALMNAHTTNAMPT | |
| SCHEMBL10823732 | 0.82 | KMT2A (0.50) | MEN1KMT2ALMNAHTTNAMPT | |
| SCHEMBL11345990 | 0.82 | FGF1 (0.55) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL10823431 | 0.80 | CHEK1 (0.45) | MEN1KMT2ALMNAHTTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |