Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670530 | 0.86 | L3MBTL1 (0.57) | HTTLMNAMAPTGAAALDH3A1 | |
| SCHEMBL10825025 | 0.80 | ENPP2 (0.50) | TDP1ALDH1A1ENPP2 | |
| SCHEMBL6194239 | 0.78 | HTT (0.61) | HTTLMNAMAPTGAAALDH3A1 | |
| SCHEMBL28335505 | 0.77 | ENPP2 (0.50) | TDP1ALDH1A1ENPP2 | |
| SCHEMBL11526803 | 0.77 | HTT (0.71) | HTTLMNAMAPTGAAALDH3A1 | |
| SCHEMBL10825043 | 0.76 | TDP1 (0.49) | HTTGAAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10825049 | 0.76 | PKM (0.44) | HTTLMNAMAPTGAAALDH3A1 | |
| SCHEMBL2333062 | 0.76 | HTT (0.61) | HTTLMNAMAPTGAAALDH3A1 | |
| SCHEMBL11434202 | 0.75 | KCNMA1 (0.43) | HTTLMNAMAPTGAATDP1 | |
| SCHEMBL11434200 | 0.75 | MEN1 (0.56) | LMNAMAPTGAAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116884-B1 | NITRO-NAPHTHYLAMINE SULPHONIC ACIDS | BAYER AG (DE) | 1986-04-09 | — | — | EP | disclosed |
| EP-0116884-A1 | Nitro-naphthylamine sulphonic acids | BAYER AG (DE) | 1984-08-29 | — | — | EP | disclosed |