Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493799 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL11493047 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL3981337 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6832911 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL28099650 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6398933 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10624515 | 0.98 | HSD17B10 (0.58) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6400208 | 0.95 | HSD17B10 (0.61) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL27281280 | 0.91 | HSD17B10 (0.49) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8398635 | 0.89 | HSD17B10 (0.68) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | BASF SE (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | BASF SE (DE) | 2017-06-29 | — | — | US | disclosed |
| US-20170036969-A1 | NITRIFICATION INHIBITORS | BASF SE (DE) | 2017-02-09 | — | — | US | disclosed |
| EP-0196805-A1 | Acylation of naphthalenes | CELANESE CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |
| US-4593125-A | In anhydrous hydrogen fluoride | CELANESE CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| US-4323714-A | Alkylation of hydroxy-substituted aromatic compounds | UOP INC. (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0035678-A2 | Process for the dyeing of carrier-free dyeable polyester fibres | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036969-A1 | NITRIFICATION INHIBITORS | NOS1, NOS2, NOS3 | HSD17B10 851/4885CYP1A2 40/4885CYP2C9 267/4885 |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | PRXL2A, NIT2, NAT1 | HSD17B10 2561/4885CYP1A2 113/4885CYP2C9 1618/4885 |
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | NAT1, PRXL2A, DDAH1 | HSD17B10 1648/4885CYP1A2 22/4885CYP2C9 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.