Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827144 | 0.92 | ALDH1A1 (0.42) | ALDH1A1ALOX15TSHRL3MBTL1HTT | |
| SCHEMBL10827660 | 0.84 | TSHR (0.52) | ALDH1A1ALOX15TSHRL3MBTL1HTT | |
| SCHEMBL10827062 | 0.81 | CTSD (0.45) | ALDH1A1ALOX15TSHRL3MBTL1HTT | |
| SCHEMBL10828363 | 0.81 | TDP1 (0.36) | ALOX15TSHRL3MBTL1PTGS2GCK | |
| SCHEMBL10827387 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL10827666 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX15TSHRL3MBTL1HTT | |
| SCHEMBL10827126 | 0.76 | TSHR (0.41) | ALDH1A1TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL10828432 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALOX15TSHRL3MBTL1HTT | |
| SCHEMBL10827670 | 0.73 | PARG (0.44) | ALOX15TSHRL3MBTL1 | |
| SCHEMBL10827391 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TSHRHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |