Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250054 | 0.82 | ALDH1A1 (0.39) | NLRP3USP2TSHR | |
| SCHEMBL10669272 | 0.80 | ALDH1A1 (0.46) | NLRP3TSHR | |
| SCHEMBL4201443 | 0.80 | PLA2G2C (0.33) | NLRP3USP2TSHR | |
| SCHEMBL10841258 | 0.78 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL10669266 | 0.78 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL112027 | 0.78 | LMNA (0.46) | NLRP3TSHR | |
| SCHEMBL635545 | 0.78 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL11316544 | 0.78 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL16449384 | 0.78 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL7156815 | 0.76 | PLA2G2C (0.37) | NLRP3USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604460-A | ANTIBIOTICS, BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1986-08-05 | — | — | US | disclosed |
| US-4533730-A | BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4504659-A | 1-Oxadethiacepham compounds | SHIONOGI & CO., LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| US-4478997-A | 1-Oxadethiacepham compounds | SHIONOGI & CO., LTD. (JP) | 1984-10-23 | — | — | US | disclosed |
| US-4443598-A | ANTIBIOTICS AND INTERMEDIATES | SHIONOGI & CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| US-4366316-A | FROM OXAZOLINOAZETIDINONE AND ACID | SHIONOGI & CO., LTD. (JP) | 1982-12-28 | — | — | US | disclosed |