SCHEMBL4201443

SCHEMBL4201443

CS(=O)(=O)CCOC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.33
NLRP3 Q96P20 1/20 0.32
USP2 O75604 1/20 0.30
TSHR P16473 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4250054 0.82 ALDH1A1 (0.39) PLA2G2CNLRP3USP2TSHR
SCHEMBL10669272 0.80 ALDH1A1 (0.46) PLA2G2CNLRP3TSHR
SCHEMBL10827151 0.80 NLRP3 (0.32) NLRP3USP2TSHR
SCHEMBL10669266 0.78 NLRP3 (0.31) NLRP3
SCHEMBL11316544 0.78 NLRP3 (0.36) NLRP3
SCHEMBL635545 0.78 NLRP3 (0.31) NLRP3
SCHEMBL112027 0.78 LMNA (0.46) NLRP3TSHR
SCHEMBL16449384 0.78 NLRP3 (0.31) NLRP3
SCHEMBL10841258 0.78 NLRP3 (0.31) NLRP3
SCHEMBL9386508 0.77 PTGS1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12467053-B2 Hybrid immunoglobulins with moving parts BIOMOLECULAR HOLDINGS LLC (US) 2025-11-11 US disclosed
EP-3284825-B1 METHODS OF PRODUCING HYBRID POLYPEPTIDES WITH MOVING PARTS BIOMOLECULAR HOLDINGS LLC (US) 2021-04-07 EP disclosed
US-20200032272-A1 HYBRID IMMUNOGLOBULINS WITH MOVING PARTS BIOMOLECULAR HOLDINGS LLC 2020-01-30 US disclosed
US-10428332-B2 Hybrid immunoglobulins with moving parts BIOMOLECULAR HOLDINGS LLC 2019-10-01 US disclosed
EP-3284825-A1 METHODS OF PRODUCING HYBRID POLYPEPTIDES WITH MOVING PARTS Capon, Daniel J. (US) 2018-02-21 EP disclosed
EP-2078040-B1 Methods of producing hybrid polypeptides with moving parts CAPON DANIEL J (US) 2017-06-28 EP disclosed
US-20160376601-A1 Hybrid immunoglobulins with moving parts BIOMOLECULAR HOLDINGS LLC 2016-12-29 US disclosed
WO-2008140477-A9 HYBRID IMMUNOGLOBULINS WITH MOVING PARTS CAPON DANIEL J (US) 2009-10-15 WO disclosed
US-20090233806-A1 Protein isolation and analysis CARR FRANCIS J 2009-09-17 US disclosed
EP-2078040-A2 HYBRID IMMUNOGLOBULINS WITH MOVING PARTS Capon, Daniel J. (US) 2009-07-15 EP disclosed
WO-2008140477-A2 HYBRID IMMUNOGLOBULINS WITH MOVING PARTS CAPON DANIEL J (US) 2008-11-20 WO disclosed
US-20080254512-A1 Hybrid immunoglobulins with moving parts BIOMOLECULAR HOLDINGS LLC 2008-10-16 US disclosed
US-7351540-B1 Protein isolation and analysis MERCK PATENT GMBH (DE) 2008-04-01 US disclosed
EP-0098729-B1 OXIME DERIVATIVES AND PROCESSES OF FORMING POLYMERIC OXIMES POLAROID CORPORATION (US) 1986-10-08 EP disclosed
US-4604460-A ANTIBIOTICS, BACTERICIDES SHIONOGI & CO., LTD. (JP) 1986-08-05 US disclosed
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US disclosed
US-4504659-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1985-03-12 US disclosed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US disclosed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12467053-B2 Hybrid immunoglobulins with moving parts IGLV6-57, FCGRT, FCGR3B PLA2G2C 498/4885NLRP3 1875/4885USP2 3965/4885
US-10428332-B2 Hybrid immunoglobulins with moving parts FCGRT, IGLV6-57, FCGR3B PLA2G2C 662/4885NLRP3 1927/4885USP2 3918/4885
US-20080254512-A1 Hybrid immunoglobulins with moving parts FCGRT, IGLV6-57, FCGR3B PLA2G2C 662/4885NLRP3 1927/4885USP2 3918/4885
US-20200032272-A1 HYBRID IMMUNOGLOBULINS WITH MOVING PARTS IGLV6-57, FCGRT, FCGR3B PLA2G2C 498/4885NLRP3 1875/4885USP2 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.