Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250054 | 0.80 | ALDH1A1 (0.39) | NLRP3 | |
| SCHEMBL10669272 | 0.78 | ALDH1A1 (0.46) | NLRP3 | |
| SCHEMBL4201443 | 0.78 | PLA2G2C (0.33) | NLRP3 | |
| SCHEMBL10827151 | 0.78 | NLRP3 (0.32) | NLRP3 | |
| SCHEMBL10841258 | 0.76 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL10669266 | 0.76 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL112027 | 0.76 | LMNA (0.46) | NLRP3 | |
| SCHEMBL11316544 | 0.76 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL635545 | 0.76 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL7156815 | 0.74 | PLA2G2C (0.37) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723152-B1 | Pyrrolobenzodiazepines | SPIROGEN SARL (CH) | 2015-02-11 | — | — | EP | disclosed |