Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827110 | 0.93 | KLK7 (0.48) | LMNAKLK7SMN1; SMN2CCKBRKDM4E | |
| SCHEMBL10827380 | 0.84 | PDE10A (0.48) | SMN1; SMN2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL10827674 | 0.82 | PDE10A (0.41) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL10827387 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL10827062 | 0.78 | CTSD (0.45) | LMNASMN1; SMN2KDM4EHPGDMEN1 | |
| SCHEMBL10827676 | 0.77 | RORA (0.45) | SMN1; SMN2KDM4EALDH1A1MAPTCTSK | |
| SCHEMBL10827107 | 0.76 | DDR1 (0.38) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10827391 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7025946 | 0.73 | ALDH1A1 (0.57) | LMNACCKBRKMT2AALDH1A1NPC1 | |
| SCHEMBL10828432 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |