Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.63 |
| ▸ | SCN1A | P35498 | 1/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131179 | 0.88 | HTR1A (0.65) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10372041 | 0.87 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL566421 | 0.85 | LTA4H (0.64) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL6356804 | 0.85 | HTR1A (0.61) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10832670 | 0.84 | DRD2 (0.47) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11105514 | 0.84 | HTR1A (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9458526 | 0.82 | ADRA1D (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11104487 | 0.82 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8132707 | 0.82 | DRD2 (0.58) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11854599 | 0.82 | ADRA2A (0.84) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579845-A | Antihypertensive cyanoguanidines | BOUCHARA S.A. (FR) | 1986-04-01 | — | — | US | disclosed |