Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835778 | 0.88 | DRD2 (0.68) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL10835725 | 0.86 | HTR1A (0.63) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL10835753 | 0.86 | DRD2 (0.69) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL10835535 | 0.85 | DRD3 (0.47) | DRD2DRD3ADRA1BALDH1A1MEN1 | |
| SCHEMBL10834873 | 0.83 | TRPV4 (0.49) | — | |
| SCHEMBL10835523 | 0.82 | HTR1A (0.58) | DRD2DRD3DRD4LMNAHTR1A | |
| SCHEMBL10835924 | 0.81 | DRD2 (0.71) | DRD2DRD3DRD4ADRA1DADRA1A | |
| SCHEMBL10835272 | 0.80 | DRD2 (0.54) | DRD2DRD3DRD4ADRA1DADRA1A | |
| SCHEMBL10834596 | 0.80 | DRD2 (0.54) | DRD2DRD3DRD4ADRA1DADRA1A | |
| SCHEMBL10836439 | 0.78 | DRD2 (0.50) | DRD2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585773-A | DIURETIC, HYPOTENSIVE | BRISTOL-MYERS COMPANY (US) | 1986-04-29 | — | — | US | disclosed |