Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835725 | 0.88 | HTR1A (0.63) | — | |
| SCHEMBL10836439 | 0.85 | DRD2 (0.50) | — | |
| SCHEMBL10834926 | 0.83 | TRPV4 (0.46) | TRPV4 | |
| SCHEMBL10834571 | 0.83 | DRD2 (0.52) | — | |
| SCHEMBL10835523 | 0.82 | HTR1A (0.58) | — | |
| SCHEMBL10956353 | 0.82 | CA1 (0.53) | — | |
| SCHEMBL10835778 | 0.80 | DRD2 (0.68) | — | |
| SCHEMBL7986385 | 0.80 | ADRA1D (0.70) | — | |
| SCHEMBL9586369 | 0.79 | ACHE (0.56) | TRPV4 | |
| SCHEMBL10835753 | 0.78 | DRD2 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585773-A | DIURETIC, HYPOTENSIVE | BRISTOL-MYERS COMPANY (US) | 1986-04-29 | — | — | US | disclosed |