Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836177 | 0.82 | S1PR1 (0.44) | S1PR1THRATHRBADRA1DABCB1 | |
| Hydrochloric Acid SCHEMBL10837925 | 0.81 | S1PR1 (0.43) | S1PR1THRATHRBADRA1DABCB1 | |
| Water SCHEMBL10836253 | 0.81 | S1PR1 (0.43) | S1PR1THRATHRBADRA1DABCB1 | |
| SCHEMBL10836583 | 0.74 | HTR1A (0.48) | ADRA1DDRD2DRD4DRD3HTR1A | |
| SCHEMBL23221226 | 0.66 | S1PR1 (0.56) | S1PR1ADRA1DDRD2DRD3HTR2A | |
| SCHEMBL10835787 | 0.66 | HTR1A (0.48) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL10901656 | 0.65 | S1PR1 (0.69) | S1PR1THRATHRBDRD4HTR2A | |
| SCHEMBL10726826 | 0.64 | ALDH1A1 (0.61) | THRATHRBDRD4MEN1KMT2A | |
| SCHEMBL11290166 | 0.62 | HTR1A (0.52) | ABCB1DRD2DRD4DRD3HTR2A | |
| SCHEMBL177063 | 0.62 | S1PR1 (1.00) | S1PR1THRATHRBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4460593-A | Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4455422-A | ANTIHISTAMINES, CNS CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |