Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.52 |
| ▸ | DRD4 | P21917 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835787 | 0.85 | HTR1A (0.48) | HTR1ADRD4DRD2DRD3HTR7 | |
| SCHEMBL10836177 | 0.81 | S1PR1 (0.44) | HTR1ADRD4DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL10837925 | 0.81 | S1PR1 (0.43) | HTR1ADRD4DRD2HTR2ADRD3 | |
| Water SCHEMBL10836253 | 0.81 | S1PR1 (0.43) | HTR1ADRD4DRD2HTR2ADRD3 | |
| SCHEMBL10838043 | 0.78 | SCN1A (0.47) | DRD4DRD2DRD3KDM4E | |
| SCHEMBL10836233 | 0.76 | HTR1A (0.56) | HTR1ADRD4DRD2HTR2ADRD3 | |
| SCHEMBL10836259 | 0.76 | HTR1A (0.53) | HTR1ADRD4DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL10837514 | 0.74 | DRD2 (0.51) | HTR1ADRD4DRD2HTR2ADRD3 | |
| SCHEMBL10838437 | 0.74 | DRD2 (0.55) | HTR1ADRD4DRD2HTR2ADRD3 | |
| SCHEMBL11832182 | 0.73 | DRD2 (0.88) | HTR1ADRD4DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57142972-A | — | — | None | — | — | JP | disclosed |
| JP-S57142972-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1982-09-03 | — | — | JP | disclosed |