Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837645 | 0.86 | HTT (0.45) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| SCHEMBL10838466 | 0.84 | HTT (0.43) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| SCHEMBL10836959 | 0.79 | HTT (0.48) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| SCHEMBL3387202 | 0.70 | ALDH1A1 (0.42) | KMT2AALDH1A1KDM4EMEN1POLB | |
| SCHEMBL10720608 | 0.67 | TSHR (0.69) | KMT2AALDH1A1KDM4EMEN1HTT | |
| SCHEMBL10838011 | 0.66 | LMNA (0.62) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| Ofornine SCHEMBL30560632 | 0.66 | LMNA (0.62) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| SCHEMBL10838059 | 0.66 | LMNA (0.62) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| Ofornine SCHEMBL120272 | 0.66 | LMNA (0.62) | KMT2AALDH1A1CYP2C9KDM4EHSD17B10 | |
| SCHEMBL6045903 | 0.65 | HPGD (0.76) | KMT2AALDH1A1KDM4EMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610991-A | Antihypertensive pyridylaminobenzamide compounds | STERLING DRUG INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | disclosed |