Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838466 | 0.91 | HTT (0.43) | HTTKMT2AALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL10838404 | 0.86 | KMT2A (0.42) | HTTKMT2AALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL10836959 | 0.84 | HTT (0.48) | HTTKMT2AALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL10839348 | 0.78 | CDC7 (0.39) | HTTKMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL10838759 | 0.75 | HTT (0.46) | HTTKMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL10987172 | 0.69 | HTT (0.49) | HTTKMT2AKDM4ETSHRMEN1 | |
| SCHEMBL10720608 | 0.68 | TSHR (0.69) | HTTKMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL13905030 | 0.68 | HTT (0.57) | HTTKMT2AALDH1A1HSD17B10TSHR | |
| Ofornine SCHEMBL120272 | 0.68 | LMNA (0.62) | HTTKMT2AALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL29944048 | 0.68 | ALDH1A1 (0.74) | KMT2AALDH1A1KDM4ETSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610991-A | Antihypertensive pyridylaminobenzamide compounds | STERLING DRUG INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | disclosed |