Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839348 | 0.80 | CDC7 (0.39) | HTTTSHRALDH1A1HPGDKDM4E | |
| SCHEMBL2484487 | 0.76 | TSHR (0.57) | HTTTSHRADRA1DADRA1AADRA1B | |
| SCHEMBL10838068 | 0.72 | L3MBTL1 (0.54) | HTTTSHRADRA1DADRA1AADRA1B | |
| SCHEMBL24484638 | 0.69 | TSHR (0.45) | HTTTSHRADRA1DADRA1AADRA1B | |
| SCHEMBL9549393 | 0.69 | NAAA (0.63) | HTTTSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6359135 | 0.69 | NAAA (0.75) | TSHRALDH1A1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL6684555 | 0.69 | P2RX7 (0.45) | HTTTSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2577570 | 0.68 | L3MBTL1 (0.64) | HTTTSHRADRA1DADRA1AADRA1B | |
| SCHEMBL28773230 | 0.68 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL10838466 | 0.68 | HTT (0.43) | HTTTSHRADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610991-A | Antihypertensive pyridylaminobenzamide compounds | STERLING DRUG INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | disclosed |