Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | HTR2B | P41595 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28994087 | 0.79 | HTR2C (0.42) | HTR2AHTR2CHTR2BKCNH2CES1 | |
| SCHEMBL7422449 | 0.68 | F2 (0.34) | — | |
| SCHEMBL7422444 | 0.68 | F2 (0.34) | — | |
| SCHEMBL10838799 | 0.66 | AR (0.34) | HTR2AHTR2CHTR2BKCNH2CES1 | |
| SCHEMBL7422361 | 0.65 | MTNR1A (0.59) | HTR2B | |
| SCHEMBL7422364 | 0.65 | MTNR1A (0.59) | HTR2B | |
| SCHEMBL9510659 | 0.65 | PNMT (0.42) | HTR2AHTR2CHTR2BKCNH2CES1 | |
| SCHEMBL15381175 | 0.64 | ESR2 (0.56) | — | |
| SCHEMBL10840037 | 0.64 | HTR2C (0.41) | HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL10838832 | 0.61 | HTR2A (0.33) | HTR2AHTR2CHTR2BKCNH2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138176-B1 | PROCESS FOR THE PREPARATION OF QUINOLINES | BASF Aktiengesellschaft (DE) | 1988-05-04 | — | — | EP | disclosed |
| US-4617395-A | Preparation of quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0138176-A2 | Process for the preparation of quinolines | BASF Aktiengesellschaft (DE) | 1985-04-24 | — | — | EP | disclosed |