Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199351 | 0.73 | — | — | |
| SCHEMBL11095529 | 0.72 | DRD4 (0.31) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL3264153 | 0.72 | NOTUM (0.36) | DRD3 | |
| SCHEMBL3601233 | 0.72 | PRMT3 (0.32) | — | |
| SCHEMBL4982963 | 0.71 | — | — | |
| SCHEMBL770764 | 0.71 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL2824470 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL27408466 | 0.68 | — | — | |
| SCHEMBL769747 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL1282892 | 0.68 | SIGMAR1 (0.30) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108892637-A | SHIP1 regulator and relative method | 阿奎诺克斯药物（加拿大）公司 | 2018-11-27 | — | — | CN | claimed |
| CN-108892637-A | SHIP1 regulator and relative method | 阿奎诺克斯药物（加拿大）公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-105164108-B | SHIP1 modulators and methods related thereto | 阿奎诺克斯药物（加拿大）公司 | 2018-07-17 | — | — | CN | disclosed |
| US-4626591-A | Trans-dl-1-alkyl-6-alkoxy-1,2,3,4,4a,5,8,8a octa-hydroquinolines | ELI LILLY AND COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| US-4540787-A | Method of preparing trans-D1-1-alkyl-6-oxodecahydroquinolines | ELI LILLY AND COMPANY (US) | 1985-09-10 | — | — | US | disclosed |