Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839656 | 0.81 | KDM4E (0.35) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL10840722 | 0.81 | AHR (0.37) | KMT2AHTR5APRCPHTR1ALMNA | |
| SCHEMBL10841145 | 0.77 | PNMT (0.34) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10838832 | 0.75 | HTR2A (0.33) | ALDH1A1CREBBPTSHRHTR2AHTR2C | |
| SCHEMBL5208272 | 0.73 | TSHR (0.49) | NOS2CREBBPPRCPLMNATSHR | |
| SCHEMBL5213527 | 0.73 | TSHR (0.49) | NOS2CREBBPPRCPLMNATSHR | |
| SCHEMBL9791471 | 0.72 | CREBBP (0.56) | MEN1ALDH1A1KMT2ACREBBPHTR5A | |
| SCHEMBL26075115 | 0.71 | TSHR (0.47) | NOS2ALDH1A1CREBBPPRCPLMNA | |
| SCHEMBL10840488 | 0.71 | PNMT (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL23253603 | 0.70 | PARP1 (0.49) | NOS2MEN1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |