Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838832 | 0.84 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840722 | 0.81 | AHR (0.37) | PNMTHTR2CHTR2B | |
| SCHEMBL10840853 | 0.74 | CNR1 (0.31) | HTR2C | |
| SCHEMBL10839656 | 0.74 | KDM4E (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840462 | 0.71 | NOS2 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL10841145 | 0.68 | PNMT (0.34) | PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL10840013 | 0.68 | HTR2C (0.40) | PNMTHTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL5213527 | 0.66 | TSHR (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL5208272 | 0.66 | TSHR (0.49) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL11332118 | 0.65 | HTR2C (0.39) | PNMTHTR2AHTR2CHTR2BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |