Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838832 | 0.84 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840462 | 0.81 | NOS2 (0.35) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL10840488 | 0.74 | PNMT (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840722 | 0.71 | AHR (0.37) | KMT2AHTR2CHTR2B | |
| SCHEMBL10841145 | 0.68 | PNMT (0.34) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL10840693 | 0.68 | LMNA (0.34) | MEN1KMT2A | |
| SCHEMBL5208272 | 0.66 | TSHR (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL5213527 | 0.66 | TSHR (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840853 | 0.65 | CNR1 (0.31) | HTR2C | |
| SCHEMBL26075115 | 0.65 | TSHR (0.47) | HSD17B10HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |