Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839656 | 0.84 | KDM4E (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840488 | 0.84 | PNMT (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL10840722 | 0.78 | AHR (0.37) | HTR2CHTR2BPOLBTSHR | |
| SCHEMBL10840462 | 0.75 | NOS2 (0.35) | HTR2AHTR2CHTR2BCREBBPALDH1A1 | |
| SCHEMBL10840853 | 0.72 | CNR1 (0.31) | HTR2C | |
| SCHEMBL10840724 | 0.68 | BRD4 (0.39) | HTR2AHTR2CHTR2BKCNH2CES1 | |
| SCHEMBL10841145 | 0.66 | PNMT (0.34) | HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL10840013 | 0.66 | HTR2C (0.40) | HTR2AHTR2CHTR2BMAPTMAPK1 | |
| SCHEMBL10840693 | 0.66 | LMNA (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL28994087 | 0.65 | HTR2C (0.42) | HTR2AHTR2CHTR2BKCNH2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |