Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840488 | 0.81 | PNMT (0.32) | HTR2CHTR2BPNMT | |
| SCHEMBL10840462 | 0.81 | NOS2 (0.35) | HTR5AKMT2ALMNATSHRTAS1R3 | |
| SCHEMBL10838832 | 0.78 | HTR2A (0.33) | TSHRHTR2CHTR2BPOLB | |
| SCHEMBL10840853 | 0.77 | CNR1 (0.31) | HTR2C | |
| SCHEMBL10841145 | 0.77 | PNMT (0.34) | KMT2ATAS1R3TAS1R1TAS1R2HTR2C | |
| SCHEMBL5208272 | 0.73 | TSHR (0.49) | LMNATSHRHTR2CHTR2BPRCP | |
| SCHEMBL5213527 | 0.73 | TSHR (0.49) | LMNATSHRHTR2CHTR2BPRCP | |
| SCHEMBL26075115 | 0.71 | TSHR (0.47) | LMNATSHRHTR2CHTR2BPRCP | |
| SCHEMBL10839656 | 0.71 | KDM4E (0.35) | KMT2AHTR2CHTR2B | |
| SCHEMBL5880335 | 0.69 | TSHR (0.45) | LMNATSHRPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |