Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841248 | 0.82 | HTR5A (0.36) | ALDH1A1TP53TSHRMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7658456 | 0.77 | DRD2 (0.35) | ALDH1A1GRK6DAONPSR1MEN1 | |
| SCHEMBL4456748 | 0.71 | ADAMTS4 (0.30) | ALDH1A1TDP1LMNAALOX15HSD17B10 | |
| SCHEMBL940184 | 0.71 | ALDH1A1 (0.50) | ALDH1A1GRK6L3MBTL1MAPTCYP1A2 | |
| SCHEMBL2068454 | 0.65 | ALDH1A1 (0.54) | ALDH1A1GRK6TSHRL3MBTL1MAPT | |
| SCHEMBL10839955 | 0.65 | ALDH1A1 (0.39) | ALDH1A1GRK6TP53TSHRDAO | |
| SCHEMBL8053689 | 0.64 | MAPT (0.41) | ALDH1A1GRK6MAPTNPSR1MEN1 | |
| SCHEMBL7216738 | 0.64 | CA12 (0.34) | — | |
| SCHEMBL10828304 | 0.64 | PDK2 (0.61) | ALDH1A1GRK6TP53TSHRDAO | |
| SCHEMBL10828059 | 0.64 | PDK2 (0.38) | ALDH1A1GRK6DAOL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |