Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29789658 | 0.83 | HTR5A (0.45) | HTR5AHTR1AHTR1DHTR2CHTR7 | |
| SCHEMBL6986075 | 0.83 | HTR5A (0.45) | HTR5AHTR1AHTR1DHTR2CHTR7 | |
| SCHEMBL10839955 | 0.79 | ALDH1A1 (0.39) | HTR2CGAA | |
| SCHEMBL10841085 | 0.78 | SLC6A2 (0.36) | HTR1AGAA | |
| SCHEMBL10839480 | 0.74 | HTR5A (0.41) | HTR5ACA1CA2CA7CA9 | |
| SCHEMBL10840441 | 0.72 | PDE7A (0.37) | CA1CA2CA7CA9 | |
| SCHEMBL29789651 | 0.72 | HTR5A (0.40) | HTR5ACA1CA2CA7CA9 | |
| SCHEMBL10840955 | 0.72 | HTR5A (0.40) | HTR5ACA1CA2CA7CA9 | |
| SCHEMBL10841141 | 0.72 | AHR (0.43) | HTR5AHTR2CADRA2AADRA2BADRA2C | |
| SCHEMBL10909385 | 0.72 | SRC (0.56) | HTR5AHTR1AHTR1DHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |