Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17272799 | 0.73 | KDM4E (0.45) | MAOAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL10587136 | 0.73 | MAPT (0.46) | MAOAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL8596062 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKDM4EDDAH1 | |
| SCHEMBL1710671 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKDM4EDDAH1 | |
| SCHEMBL605891 | 0.69 | KDM4E (0.52) | MAOAABCG2MAPTALDH1A1LMNA | |
| SCHEMBL31568235 | 0.69 | MAOA (0.40) | MAOAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL11570093 | 0.69 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAKDM4EDDAH1 | |
| SCHEMBL1478515 | 0.68 | ABCG2 (0.61) | MAOAABCG2MAPTALDH1A1KDM4E | |
| SCHEMBL29443518 | 0.68 | ABCG2 (0.61) | MAOAABCG2MAPTALDH1A1KDM4E | |
| SCHEMBL10980881 | 0.68 | PARP1 (0.49) | MAPTALDH1A1LMNAKDM4EDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949650-B1 | Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one | SHOUGUANG SYNTECH FINE CHEMICAL CO LTD (CN) | 2017-10-11 | — | — | EP | disclosed |
| US-9334248-B2 | Synthetic method for the preparation of 1, 2-benzisothiazolin-3-one | SHOUGUANG SYNTECH FINE CHEMICAL CO., LTD. (CN) | 2016-05-10 | — | — | US | disclosed |
| EP-2949650-A1 | Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one | Shouguang Syntech Fine Chemical Co., Ltd. (CN) | 2015-12-02 | — | — | EP | disclosed |
| US-20150336910-A1 | SYNTHETIC METHOD FOR THE PREPARATION OF 1, 2-BENZISOTHIAZOLIN-3-ONE | SYNTECH EURO LIMITED (GB) | 2015-11-26 | — | — | US | disclosed |
| US-4590196-A | NON-OPIATE | BRISTOL-MYERS COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336910-A1 | SYNTHETIC METHOD FOR THE PREPARATION OF 1, 2-BENZISOTHIAZOLIN-3-ONE | TST, AQP1, BZW1 | MAOA 2847/4885ABCG2 766/4885MAPT 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.