Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 13/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 8/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004230 | 0.80 | MMP1 (0.46) | MMP1MMP2MMP3MMP8FDPS | |
| SCHEMBL578487 | 0.74 | FDPS (0.33) | MMP1MMP2MMP3MMP8FDPS | |
| SCHEMBL14229497 | 0.72 | CA1 (0.48) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL18486528 | 0.71 | GGPS1 (0.52) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL9070271 | 0.71 | GGPS1 (0.52) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL18384478 | 0.71 | CA1 (0.52) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL7697441 | 0.71 | FAAH (0.52) | FDPSGGPS1 | |
| SCHEMBL6244933 | 0.70 | MMP1 (0.52) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL6057133 | 0.70 | CA12 (0.50) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL10902877 | 0.69 | FDPS (0.48) | FDPSGGPS1AGTR1OPRM1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564477-A | DOLICHOL INTERMEDIATE | KURARAY CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0087136-B1 | NOVEL POLYPRENYL COMPOUNDS, METHOD OF PRODUCING THE SAME AND THEIR USE IN DOLICHOL PRODUCTION | KURARAY CO., LTD. (JP) | 1985-07-31 | — | — | EP | disclosed |
| EP-0087136-A2 | Novel polyprenyl compounds, method of producing the same and their use in dolichol production | KURARAY CO., LTD. (JP) | 1983-08-31 | — | — | EP | disclosed |