Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004230 | 0.80 | MMP1 (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL6614297 | 0.79 | — | — | |
| SCHEMBL10850693 | 0.74 | MMP1 (0.53) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL6051813 | 0.73 | FDPS (0.37) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL282438 | 0.73 | FDPS (0.37) | FDPSGGPS1 | |
| SCHEMBL3281290 | 0.73 | FDPS (0.37) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL2857618 | 0.71 | GGPS1 (0.37) | FDPSMMP1MMP2MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL4158783 | 0.71 | FDPS (0.36) | FDPSGGPS1 | |
| SCHEMBL410826 | 0.71 | FDPS (0.39) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL2298232 | 0.71 | FDPS (0.36) | FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410273-B2 | Cyclic compound having substituted phenyl group | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| EP-2418203-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-4639450-A | LIVER DISORDERS | EISAI CO., LTD. (JP) | 1987-01-27 | — | — | US | disclosed |
| US-4564477-A | DOLICHOL INTERMEDIATE | KURARAY CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0087136-B1 | NOVEL POLYPRENYL COMPOUNDS, METHOD OF PRODUCING THE SAME AND THEIR USE IN DOLICHOL PRODUCTION | KURARAY CO., LTD. (JP) | 1985-07-31 | — | — | EP | disclosed |
| US-4456603-A | Polyprenylcarboxylic acid amides useful for treating liver dysfunction | EISAI CO., LTD. (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0087136-A2 | Novel polyprenyl compounds, method of producing the same and their use in dolichol production | KURARAY CO., LTD. (JP) | 1983-08-31 | — | — | EP | disclosed |
| US-4388237-A | NEUROLEPTIC, SEDATIVE, HYPNOTIC, ANALGESIC, ANTIDEPRESSANT | BASF AKTIENGESELLSCHAFT (DE) | 1983-06-14 | — | — | US | disclosed |
| US-4336192-A | ANALGESICS, SEDATIVES, ANTICHOLINERGIC AGENTS, ANTIEMETICS | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-22 | — | — | US | disclosed |
| EP-0019172-A1 | 6-Substituted 11-alkylene-morphantridines, process for preparing them and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0019157-A1 | 5,6-Dihydro-11-alkylene-morphanthridin-6-ones and process for their preparation | BASF Aktiengesellschaft (DE) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | BMP2, BMP4, BMP6 | FDPS 3307/4885MMP1 81/4885MMP2 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.